Gastrointestinal (GI): NSAIDs that block COX-1 action have correlations with GI difficulties as a result of inhibition on the synthesis of gastroprotective agents such as PGE2 and other prostaglandins. This inhibition brings about diminished mucin output by gastric epithelial cells, less bicarbonate secretion, and fewer epithelial cell turnover, amongst other https://klausa641ibd0.wonderkingwiki.com/user