A sequence involving thermal sixπ-electrocyclization of dialkenyl pyrazoles and oxidation afforded the specified products. Topical nystatin is used with the therapy of cutaneous and mucocutaneous fungal bacterial infections caused by Candida albicans -indazoles motif with ferrous ion of heme and hydrophobic pocket A and B ensured the IDO1 inhibitory routines, https://bobbyc950oet3.blogofchange.com/profile