As opposed to CB2, CB1 receptors are linked to Exclusive membrane microdomains, named “lipid rafts” (LR) that modulate CB1-dependent signaling pathways. The purposeful romance amongst CB1 and LR is affected by cholesterol content material; specifically, membrane cholesterol enrichment in both primary and immortalized cell lines minimizes the binding to CB1 https://remingtonvemtc.iyublog.com/32195897/examine-this-report-on-endocannabinoid-system