An Formal Web-site of The us governing administration. Here's how you recognize we are Formal. dot gov icon Nonabsorbed ursodiol passes in to the colon where by it is mostly seven-dehydroxylated to lithocholic acid. Some ursodiol is epimerized to chenodiol (CDCA) via a 7-oxo intermediate. Chenodiol also undergoes seven-dehydroxylation https://www.youtube.com/watch?v=A07qHOeWON8